Multiple Sclerosis is a chronic disease that affects the central nervous system, especially the brain, spinal chord, and optic nerves.
| Aetna | OK for Standard |
| Aflac | OK for Standard |
| Americo | Decline |
| Living Promise | Decline if diagnosed with, treated for or taken medications for in the last 4 years. |
| Royal Neighbors | Allowed |
| Corebridge | Decline |
| TransAmerica | Allowed for Select Decline for Premier |
| American Amicable/Occidental | Decline for Immediate if medically diagnosed, treated, or hospitalized for within the past 3 years |
| GTL | Not specifically mentioned |
