Down Syndrome is a congenital disorder arising from a chromosome defect, causing intellectual impairment and physical abnormalities, including short stature and a broad facial profile.
| Aetna | Not specifically mentioned |
| Aflac | Not specifically mentioned |
| Americo | Decline |
| Living Promise | Decline |
| Royal Neighbors | Not specifically mentioned |
| Corebridge | Not specifically mentioned |
| TransAmerica | Decline |
| American Amicable/Occidental | Not specifically mentioned |
| GTL | Not specifically mentioned |
